CBD Hype: Is it Worth Buying?

cbd products

Share This Post

The triumphant stories of many novel medications can be rooted in someone’s misfortune.

Such was the story of 5-year old Charlotte Figi, who back in 2013 had as many as 50 seizures a day. 

Charlotte was diagnosed with a very rare form of epilepsy called Dravet Syndrome.

She had cognitive and motor delays, had a feeding tube inserted, and struggled with daily activities all because of the number of seizures she had each day.

As stories go, there was a moment of hope. Charlotte’s mother stumbled upon a story of a child in California who used medical marijuana for a similar issue.

She was quick to research marijuana’s anti-seizure effects in the scientific literature. The literature specifically pointed to cannabidiol (CBD), a non-psychoactive component of the Cannabis plant as the probable anti-seizure compound.

The Figi family lives in Colorado, where medical marijuana has been legal since the year 2000.

They identified a strain of Cannabis at a local dispensary that contained just the right amount of CBD and no trace of the psychoactive compound delta-9-tetrahydrocannabinol (Δ9-THC; commonly known just as THC). 

With the blessings of the state of Colorado and Charlotte’s doctors, the parents began using purified CBD from the unique Cannabis strain.

To everyone’s surprise, after a few weeks of increasing the CBD to an effective dose, Charlotte was finally seizure-free for as much as an entire week. 

Charlotte went from having 50 episodes a day to only about 2-3 episodes a month. Her story received recognition via a documentary called “Weed”

How Does CBD Work to Control Seizures?

Charlotte’s story sparked countless other sufferers of epilepsy to try CBD… and many reported more control over their seizures. 

It has to be noted that these patients, including Charlotte, continued to take at least one other medication from their original epilepsy treatment regimen.

CBD was an addition to therapy, not a single therapeutic agent. 

Following Charlotte’s story and subsequent scientific studies, the FDA approved a specific oil-based solution of CBD called Epidiolex® in 2018. 

  • Epidiolex® is pure CBD extracted directly from the Cannabis plant 
  • It is the first natural product to be approved by the FDA for the treatment of rare forms of epilepsy: Lennox-Gastaut syndrome and Dravet syndrome

We surprisingly still know very little about how CBD specifically works to prevent seizures.

Scientists know that it likely has nothing to do with cannabinoid receptors found throughout the central nervous system; although, some alternative ideas are emerging

More research is needed to better understand this new use of CBD and its potential for other medical conditions. 

Other Health Effects of CBD

Humans have used cannabis for millennia. We know this because Egyptians, Assyrians, and multiple Asian cultures left ancient texts that describe the use of Cannabis

We know that the cannabis plant originated somewhere in Central Asia and was first cultivated there, possibly in present-day Mongolia

Cannabis was used throughout human history for:

  • Religious ceremonies 
  • Medicinal purposes 
  • Making of textiles 
  • Euphoric effects 
  • Consumption

The emergence of new technologies capable of extracting individual ingredients from Cannabis helped spread the use of these compounds.

Thanks to such developments, we know that THC is the key molecule that is psychoactive, while CBD is not. 

CBD was first identified in 1930, but it remained fairly unpopular until Charlotte Figi used it to control her seizures.

Questions are multiplying around CBD’s other health effects. Naturally, there are already countless claims pointing to CBD’s almost magical properties. 

But – are they backed up by science? 

There is currently insufficient or inconsistent evidence to make a definite recommendation on most of these claims, but the most promising studies pertain to: 

  • Movement disorders 
  • Insomnia
  • Peripheral neuropathy
  • Social anxiety disorder

Clinical studies use very precise doses ranging from 2.5 mg per kilogram of body weight twice daily, to a fixed-dose of 600 mg; so, each studied result is tied to a very specific dose.

A higher dose will also not translate to a higher benefit. Instead, the higher the dose, the higher the likelihood of experiencing adverse effects; the desired effect usually levels off much sooner

We know that CBD can damage the liver thanks to the studies that put Epidiolex® on the market.

Patients with baseline liver disease should not use Epidiolex®. Since Epidiolex® is pure CBD, one should expect that this recommendation extends to any CBD product. 

Our favorite wellness products and recommendations

CBD MD Broad Spectrum Gummies (900+ reviews of 4.5 🌟s )

>>> Special Deals CLICK HERE

CBD MD Broad Spectrum CBD Oil ((970+ reviews of 4.5 🌟s )

>>> Special Deals for OIL CLICK HERE

Broad Spectrum Formula: Includes CBD, CBG, and CBN, THC-Free, Derived from USA-grown hemp, Tested by independent ISO 17025 certified labs for quality and consistency.

**If you’re just beginning on your CBD wellness journey, please carefully read labeling and recommendations on daily intake.

CBD can cause some other problems:

  • Somnolence 
  • Decreased appetite
  • Diarrhea 
  • Fatigue 
  • Multiple drug interactions
    • Clopidogrel, clobazam, and warfarin are examples of such interactions 
    • More interactions are being identified, as more information is collected
    • Another problem with CBD is that it can cause birth defects, so pregnant women should avoid CBD.

Why Can I Buy CBD in a Store, but Not THC?

A person can purchase CBD without a prescription anywhere in the country, thanks to the Farm Bill of 2018

The bill changed the way we define “marijuana,” which itself is defined as any part of the Cannabis plant.

Any Cannabis plant with less than 0.3% of THC is referred to as hemp and can be used for agricultural purposes.

Marijuana is still an illegal substance in the eyes of the federal government, while THC is restricted.

CBD in the form of Epidiolex® is also restricted because it is made from non-hemp Cannabis. CBD found on store shelves is made from hemp. 

Finding the Right CBD Products.

There has been some controversy regarding CBD products: 

There are some steps you can take to ensure you’re getting the right product with the right amount of CBD:

  • Good quality products will often have a certificate of purity given by an independent lab that verifies how much CBD is in the bottle that you are purchasing. 
  • This way, you will also be able to know whether your product contains any impurities or toxins like pesticides

The question on many people’s minds is, “should I spend money on this and will it even help?”

Importantly, what is “it” that you are trying to improve? Since we still lack good quality studies, there is no proof “it” will be improved.

Also, many CBD products can be pricey, which is not limited to those with purity certificates. Another important factor to remember is that many CBD products contain different strengths of CBD. 

Lastly, as with all-natural products, before making a purchase, it is a good idea to ask these two questions:

  • Will it help? 
  • Will it cause harm?

Conclusion

We will continue to learn much more about CBD as research grows. So far, we can name a few specific positive and negative effects of this compound.

For Charlotte and her family, the positive effects outweigh any potential side effects as the number of her seizures fell significantly. 

With time, we will learn more about CBD’s benefits and side effects. Until then, CBD should be used with caution and vigilance.

Be aware of new evidence and, before you take or use any CBD; make sure you consult your healthcare provider first. Afterward, if you decide to acquire CBD products, always get your product from a trusted source. 

Reference List

1. Maa E, Figi P. The case for medical marijuana in epilepsy. Epilepsia. 2014;55(6):783-786. doi:10.1111/epi.12610

2. Sanjay G. Why I changed my mind on weed. CNN. August 8, 2013. Accessed July 22, 2020. https://www.cnn.com/2013/08/08/health/gupta-changed-mind-marijuana/index.html

3. Gray RA, Whalley BJ. The proposed mechanisms of action of CBD in epilepsy. Epileptic Disord. 2020;22(S1):10-15. doi:10.1684/epd.2020.1135

4. Zuardi AW. History of cannabis as a medicine: a review. Braz J Psychiatry. 2006;28(2):153-157. doi:10.1590/s1516-44462006000200015

5. Pisanti S, Bifulco M. Medical Cannabis: A plurimillennial history of an evergreen. J Cell Physiol. 2019;234(6):8342-8351. doi:10.1002/jcp.27725

6. VanDolah HJ, Bauer BA, Mauck KF. Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clin Proc. 2019;94(9):1840-1851. doi:10.1016/j.mayocp.2019.01.003

7. What You Should Know About Using Cannabis, Including CBD, When Pregnant or Breastfeeding. U.S. Food and Drug Administration. Accessed July 22, 2020.
https://www.fda.gov/consumers/consumer-updates/what-you-should-know-about-using-cannabis-including-cbd-when-pregnant-or-breastfeeding

8. Hemp Production and the 2018 Farm Bill. U.S. Food and Drug Administration. July 25, 2019. Accessed July 22, 2020.

https://www.fda.gov/news-events/congressional-testimony/hemp-production-and-2018-farm-bill-07252019

9. FDA, FTC warn company marketing unapproved cannabidiol products with unsubstantiated claims to treat teething and ear pain in infants, autism, ADHD, Parkinson’s and Alzheimer’s disease. U.S. Food and Drug Administration. October 22, 2019. Accessed July 22, 2020.
https://www.fda.gov/news-events/press-announcements/fda-ftc-warn-company-marketing-unapproved-cannabidiol-products-unsubstantiated-claims-treat-teething

10. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD. U.S. Food and Drug Administration. Accessed July 22, 2020.
https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis

medically reviewed and fact checked
Sesame Care

Find the best price for great doctors and specialists

  • Thousands of doctors and specialists
  • $13,000,000+ saved by patients
  • 95% patient satisfaction
  • 4.3 on TrustPilot
     

Popular Destinations

Health

Medication

Telehealth Reviews

Shop

Pharmacist Membership

About Us

Pharmacy Near Me

Recent Articles

The Top 7 Best CBD Lotions of 2023

CBD, or cannabidiol, is a cannabinoid that is found in cannabis and hemp plants. It has many supposed beneficial properties for the skin, making it a popular ingredient in skincare products such as CBD lotions, creams, and salves which are becoming more and more popular as people learn about the benefits they can provide including as a pain cream option. In this article, we will discuss the top 7 best CBD creams of 2022 and we will also answer some common questions about using CBD lotions and creams on your skin, any precautions that may be necessary when using these topical products, and additional ingredients that could prove beneficial to your health.

Read More »

CBD Topical Cream for Blemishes

If you are tired of dealing with sore, spotty skin and it is a problem that you still experience on a daily basis, now is the time to take action that will give you lasting effects. In this article, we will be looking at the different types of skin blemishes and how to effectively treat them using topical CBD cream.

Read More »

Share On:

Subscribe To Our Newsletter

Get updates and learn from the best

More To Explore

How Often Should You Get an Eye Exam?

There is no “one size fits all” answer when it comes to how often you should get an eye exam, as the recommended frequency

The different types of lie bumps: Transient lingual papillitis, fungiform papillae, and other forms

Transient lingual papillitis is a condition where there are transient swellings on your tongue called lie bumps. They can be caused

Iron Infusions: Everything You Need to Know

Iron-deficiency anemia is a common condition that can cause fatigue, shortness of breath, and other health problems. If you are suffering from iron-deficiency anemia,

What Is Genomic Medicine?

Genomic medicine uses our genetic information to provide individualized health care. Various gene therapies can potentially cure rare diseases or conditions. Genetic testing allows

Chigger Bite: Everything You Need to Know 

Do you know what chiggers are? If not, you're not alone. Many people have never heard of chiggers before, but they can be a

What Are the Benefits of Manuka Honey?

Manuka honey is a unique type of honey that is produced in New Zealand and Australia as it is made by bees from the

How Often Can I Take Tylenol?

We’ve all suffered from mild to moderate pain or a fever at some point in our lives, and for many of us, we’ve likely

Coffee: Potential Benefits and Adverse Effects

In this article, we will explore coffee's history, its potential benefits, and if it is safe for everyone to consume.

Parosmia: What it is, Symptoms, Causes, and Treatment

Parosmia is an olfactory disorder where you have a distorted perception of smell and you may smell odors differently than you should. It can

What Is Levofloxacin?

Whether you’re currently fighting off pneumonia, have recently been exposed to inhalational anthrax, or are hoping to prevent infection with the plague (yes, that

Brown Recluse Spider Bites: What You Need to Know

In this article, we will discuss the symptoms of being bitten by a brown recluse spider, when to seek medical attention, and how to

What Is the Drug Levofloxacin Used For?

What happens when your doctor prescribes an antibiotic for a minor infection and it doesn’t work, or you come down with a serious case

Comparison of Azithromycin and Clarithromycin

Azithromycin and clarithromycin are both macrolide antibiotics used to treat a number of different bacterial infections, including upper respiratory tract infections, lower respiratory tract

MCHC: What It Is, Symptoms, Causes, Treatment, and More

Mean corpuscular hemoglobin concentration (MCHC) is a measure of the average amount of hemoglobin in red blood cells with hemoglobin being responsible for transporting

What are the Symptoms of Coffee Withdrawal?

Due to the prevalence of coffee, tea, soft drinks, and energy drinks, caffeine is one of the most popular drugs in the world and

Everything You Ever Wanted to Know About Quercetin

Quercetin is a powerful antioxidant and quercetin supplements are often taken as a way to support good health. Quercetin can also

How Much Does the Shingrix Vaccine Cost?

About 99 percent of American adults have had chickenpox, and many incorrectly assume that this makes them immune to shingles later in life. Shingles,

All You Need to Know About Ringworm: Symptoms, Causes, Diagnosis, and Treatment

Ringworm is a fungal infection that can be seen on the skin. It can affect both children and adults, but it's most common in

CBD Oil: What You Need to Know

CBD oil is a popular natural remedy used for many common ailments. CBD is short for cannabidiol and it is one of over 100 chemical

The Top 7 Best CBD Lotions of 2023

CBD, or cannabidiol, is a cannabinoid that is found in cannabis and hemp plants. It has many supposed beneficial properties for the skin, making